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Never before have two revolutions with so much potential to save and prolong human life occurred simultaneously. The converging, synergistic power of the biochemical and digital revolutions now allows us to read every letter of life’s code, create precisely targeted drugs to control it, and tailor their use to individual patients. Cancer, diabetes, Alzheimer’s and countless other killers can be vanquished—if we make full use of the tools of modern drug design and allow doctors the use of modern data gathering and analytical tools when prescribing drugs to their patients.
But Washington stands in the way, clinging to outdated drug-approval protocols developed decades ago during medicine’s long battle with the infectious epidemics of the past. Peter Huber, an expert in science, technology, and public policy, demonstrates why Washington’s one-size-fits-all drug policies can’t deal with diseases rooted in the complex molecular diversity of human bodies. Washington is ill-equipped to handle the torrents of data that now propel the advance of molecular medicine and is reluctant to embrace the statistical methods of the digital age that can. Obsolete economic policies, often rationalized as cost-saving measures, stifle innovation and suppress investment in the medicine that can provide the best cures at the lowest cost.
In the 1980s, an AIDS diagnosis was a death sentence, until the FDA loosened its throttling grip and began streamlining and accelerating approval of life-saving drugs. The Cure in the Code shows patients, doctors, investors, and policy makers what we must now do to capture the full life-saving and cost-saving potential of the revolution in molecular medicine. America has to choose. At stake for America is the power to lead the world in mastering the most free, fecund, competitive, dynamic, and intelligent natural resource on the planet—the molecular code that spawns human life and controls our health.
- Sales Rank: #801441 in eBooks
- Published on: 2013-11-12
- Released on: 2013-11-12
- Format: Kindle eBook
From Publishers Weekly
Digital and biochemical revolutions have made it possible to decode what ails us and help determine the remedy—if only Washington and the FDA would get out of the way—argues Huber, a lawyer and senior fellow at the Heritage Foundation, in this provocative, optimistic look at modern medicine. He envisions a free-market ideology for drug development and usage that, thanks to digital technology, will cheaply design new drugs and predict how well they perform and on whom. But Huber, who popularized the term junk science with his 1991 book Galileo's Revenge: Junk Science in the Courtroom, believes Washington nudges doctors away from the Hippocratic oath to prescribe regimens for the good of my patients and toward veterinarian ethics—the sick dog's treatment is determined by the master's willingness to pay. There's no middle ground in the war between the 20th and 21st century medicine, Huber believes—we must choose between medicine that deals with biochemical reality or is favored by crowd doctors who cling to the view that if they scrutinize, track, certify, and choreograph things just right, they can deliver better medicine to all from afar. Huber's challenge is sure to spark controversy as the U.S. adapts to the Affordable Care Act. (Nov.)
From Booklist
Our ability to read the genetic code heralds a transformation of modern medicine. Yet many potential medical miracles remain throttled. Antiquated and stifling regulations and policies presently handcuff the evolution of molecular medicine. Huber, a senior fellow at the Manhattan Institute for Policy Research, pleads for reforming the drug licensing system and advocates “a culture of discovery and creativity that is willing to take risks and invest patiently in the future.” He cites Herceptin for breast cancer, Gleevec for chronic myelogenous leukemia, and a cocktail of antiviral agents for HIV as examples of the might of molecular medicine. He blames a “muddled and often self-contradictory legal regime”—which includes federal government agencies (notably the FDA), insurance company guidelines, judges, and trial lawyers—for suffocating the advancement of molecular science. Presently, the development of new drugs and vaccines is often a dawdling, more expensive than necessary, and sometimes volatile process. Although Huber’s discussion of the topic is at times dense, his ardor for invigorating pharmaceutical progress is apparent on every page of this scholarly work. --Tony Miksanek
Review
“[An] urgent, compelling account of how 21st-century medicine is being hampered by a regulatory regime built for the science of the 20th century.”
—Wall Street Journal
“[An] exciting and authoritative review of accelerating advances in personalized medicine.”
—Barron’s
“Spotlighting an area where federal laws and regulations lag far behind technological innovation, the author, a Manhattan Institute senior fellow, maintains that medicine’s rapidly developing capacity to decode individual human genomes and tailor patients’ treatments accordingly – as with breast cancer – is being hindered by...‘outdated drug-approval protocols developed decades ago during medicine’s long battle with the infectious epidemics of the past.’”
—Pittsburgh Tribune-Review
“[Huber is] one of the few men walking the Earth who could write a book about FDA reform that is not only profitable but pleasurable to read. The book is exciting, in that it suggests possibilities for significant improvements in our ability to treat terrifying diseases in the near future; but it is also depressing, because its sophisticated analysis – in flying so far above regulation-deregulation and government-market binaries that dominate so many of our policy debates – cannot help but draw one’s attention to the intellectual poverty of Washington’s practically pre-Copernican approach to important policy decisions.... The book is sprinkled liberally with sentences that are thought-provoking gems, each worthy of an essay of its own.... [A] very rich book.”
—National Review
“Our ability to read the genetic code heralds a transformation of modern medicine. Yet many potential medical miracles remain throttled….[Huber’s] ardor for invigorating pharmaceutical progress is apparent on every page.”
—Booklist
“Intriguing.”
—Kirkus Reviews
“A provocative, optimistic look at modern medicine… Huber’s challenge is sure to spark controversy as the U.S. adapts to the Affordable Care Act.”
—Publishers Weekly
“A must read for physicians, patients, biotech investors, and healthcare politicians, The Cure in the Code is the most important policy book of the decade, and it could only have been written by Peter Huber, a polymathic master of both the deadly menace and huge promise of bioscience, and scathing critic of the blindness of healthcare bureaucracy.”
—George Gilder, author of Knowledge and Power: The Information Theory of Capitalism
“A thoughtful and compelling account of how the federal government’s current regulatory science is not only outdated, but risks hampering scientific efforts to combat diseases at the molecular level. Marshaling insights from medicine, law, and economics, Huber makes an urgent case for how to improve the drug and therapy regulatory system to better equip physicians with innovative treatments that meet critical patient needs.”
—Tom Coburn, M.D., United States Senator from Oklahoma
“Peter Huber is one of only a handful of public intellectuals with a deep understanding of science, economics, and the law. In The Cure in the Code, Huber explains scientific advances in molecular biology and genetic engineering, the economics of pharmaceuticals and medicine, and the intersection of all of these with FDA law and policy. This is a key guide to the promise of personalized medicine—personalized down to the genetic level—and also to the policies that can deliver that promise.”
—Alex Tabarrok, Professor and Bartley J. Madden Chair in Economics, George Mason University
“Peter Huber has eloquently portrayed the transition of medicine from art to science in the 21st century. But The Cure in the Code offers much more as he illuminates the changes that must occur in the research, regulatory, reimbursement ecosystem if the promise of cures is to be fulfilled.”
—Andrew von Eschenbach, Commissioner of the U.S. Food and Drug Administration (2005-2009)
Most helpful customer reviews
0 of 0 people found the following review helpful.
It is like peering through a window at the future of medicine and medical treatments
By LitPick Student Book Reviews
Thought-provoking, insightful, and concerning in light of the current changes in healthcare which will stand in the way of "sniffers" and individualized cures for the diseases of today and tomorrow.
22 of 23 people found the following review helpful.
life and death
By John Thorne
This is a well-written and important book on the future of medicine and regulation of medicine. Don't confuse it with the debates on the Affordable Care Act; it's about the regulatory impediments to investment in and approval of new medicines. Like Huber's earlier books, this one has lots of interesting stories (some funny, many tragic) to make the broader points concrete and memorable. The opening chapter is as tightly written and compelling as Dawkins's Selfish Gene.
8 of 8 people found the following review helpful.
When I Got To Be 64 Today ... I Started Thinking About Being 104
By George E. Jones
The Cure in the Code book is exciting in the new paradigm of what mankind can now start to think about in a serious way .... partial Victory Over Mortality.
It's about Mr. Huber's scholarly take on HealthSpan via molecular medicine break throughs applied in personalized and individualized ways to the parts of our DNA which regulate the Aging Process and our HealthSpan.
The biggest impediment to improving our HealthSpan is the U.S. Government and in particular the bureaucratic early 1900 mindset at the FDA.
If President Obama wanted to make a seismic change there he should appoint some like Peter Huber to head the FDA,
Watch this video then buy this book. [...]
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